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Hurler Syndrome The Eyes The accumulation of GAGs in the cornea (the clear, front covering of the eyes) leads to corneal clouding. This clouding usually begins during the first year of life and may interfere with vision, especially in dim light. Corneal transplantation (surgery to replace the damaged corneas) may be done to correct this problem.
Vision problems may also be caused by GAG accumulation in the retina (the layer of the eye which receives images and transmits them to the brain) or by glaucoma (increased pressure within the eye). Retinal damage may cause night blindness, which may be helped with the use of a night-light. Monitoring/ManagementIndividuals with Hurler syndrome should see an ophthalmologist (eye doctor) periodically to monitor vision and correct problems as needed.
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