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Certificate Program in Biomedical Research (CPBR)

Faculty Supervisors:

Daniel H. Lowenstein, M.D.
Professor of Neurology
Director, Physician-Scientist Education and Training Programs
Director, Office of Student Research (SOM)

Catherine Lomen-Hoerth, M.D., Ph.D.
Assistant Professor of Neurology
Associate Director, Office of Student Research (SOM)

Objectives & Curriculum:
Recognizing the national and state-wide need to train physician-scientists who have the ability and commitment to advance the knowledge base and practice of medicine, the UCSF Certificate Program in Biomedical Research (CPBR) is designed to facilitate opportunities for medical students to pursue full-time research for one or more years beyond the standard four year curriculum. Students who apply to the CPBR must have a well-defined plan for a high quality research project that will be carried out full-time under the careful supervision of a faculty mentor/advisor. Furthermore, the plan must be submitted to and approved by the School’s M.D. with Thesis Committee, which will assign a three-member faculty committee to oversee the student’s progress, and help the student in the preparation and completion of a written thesis. The minimum duration of the research project must be one year, with the option to extend for additional academic quarters or full years as desired or needed.

In addition to full-time work on the research project, students will attend the weekly medical student research journal club and the monthly “Pathways to Discovery” lecture series that are scheduled throughout the academic year. Specifically, students are required to participate in a minimum of 15 journal club meetings and to make at least one journal club presentation. Also, students are required to attend at least 4 of the “Pathways to Discovery” lectures. Students will also be encouraged to attend other research seminars that are available to the UCSF community throughout the year. Students pursuing clinical, patient-oriented or so-called “translational” research (as determined by the Director of the Office of Student Research) will be required to take the Designing Clinical Research (DCR) course in held in August each year, and they will also have full access to various programs organized through the Doris Duke Clinical Research Fellowship program based at UCSF.

Documentation of attendance at these various educational components of the CPBR will be provided by the student in the form of a signed document to be submitted concurrent with submission of the research thesis (i.e. February 15th of the year of graduation). Although this documentation will be carried out under the aegis of the medical school’s honor code, faculty in the Office of Student Research regularly attend the various activities listed above and will be able to monitor attendance of students as well.

The requirement of a full-year of research along with additional educational experiences makes the CPBR distinct from the current M.D. with Thesis Program, which has no specific requirements for the duration of the research experience or any additional training. The faculty leadership of the Office of Student Research believe that the CPBR program will substantially raise the quality of the overall educational experience for students interested in a serious exploration of a career path in biomedical research. At the same time, by requiring completion of the M.D. with Thesis program, the CPBR will take advantage of a pre-existing, highly successful mechanism for overseeing the quality of the research experience itself.

Length of Program:
The CPBR requires a minimum commitment to twelve (12) months of full-time research. In terms with the Office of Admission and Registrar, this translates to four (4) consecutive quarters. Although this can begin at any time during the year, it is expected that most students will begin their program between June and September.

Student Eligibility:
Any UCSF medical student in good academic standing who has designed a plan for a high quality research experience is eligible for the program. In most cases, students will opt for the CPBR in the beginning or middle of the 3rd year of the medical school curriculum; i.e. after the completion of all pre-clinical studies and electives, and during their clinical rotations. Preliminary review of the student’s qualifications and research proposal will be done by the director or associate director of the Office of Medical Student Research. Once approved at this level, the proposal will then be submitted to the MD with Thesis committee, which will determine whether any revisions are required before formally accepting the student into the M.D. with Thesis Program. Acceptance as an M.D. with Thesis candidate will constitute approval for participation in the CPBR. (For details about the M.D. with Thesis Program)

Program Requirements:
Completion of the CPBR will require:

  • Completion of all requirements of the M.D. with Thesis Program (i.e. completion of a thesis which is formally approved by a 3-person thesis committee);
  • Attestation by the student’s faculty research mentor/advisor that the student has successfully completed a full year of research activity;
  • Documentation by the student of the educational activities attended outside of the research experience itself; and
  • Review and final approval by the director and associate director of the Office of Student Research.

It is anticipated that approximately 15-20 students will opt for the CPBR each year.

Financial Support:
Students pursuing a full year of research have a number of potential sources for funding. Most students seek to obtain extramural grants, including the Howard Hughes Medical Institute Research Fellowship, the Doris Duke Charitable Foundation Fellowship, the Genentech Fellowship, the PACCTR Fellowship and others. These funds are used primarily as a stipend to cover living expenses for the year. In some of these programs, additional funds are provided for payment of various fees required by the school. For students who do not obtain fellowships, other options include Quarterly Research Grants from the Office of Student Research and financial support provided directly by their mentor.

Students participating in the CPBR will be enrolled at UCSF at a level that provides access to Central Student Services (e.g., Admission and Registration, Student Financial Services) and direct services such as membership in Millberry Union, access to the library, and Student Health Services. In addition, enrollment will include coverage for health, liability and disability insurance. Given the high priority by the School of Medicine for fostering career development in academic medicine and biomedical research, most (if not all, depending on the number of students) of the annual cost for enrollment, which is expected to be approximately $6,800 in AY ’07-08, will be provided for by the Office of Student Research.

Updated: April 4, 2008
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